In order to enhance the efficiency of Loran-C monitor system, overcome the shortage of monitor result based on simple message, this paper design an monitor system with NI PXI. First, construct the system based on PXI-5922 and PXI-8336. Second, monitor technique is given, then, implemented the experiment in fixed position. After that, comparing the results of inspection station with this system, it concluded that designed monitor system has the advantage of monitor veracity, expansibility, exploiture and update of software.