Aviation weapons and equipments have been developed by leaps and bounds in recent years, airborne precision-guided weapons have a major breakthrough from scratch, but the use of active equipment in the use of conditions and the use of attack envelope cannot meet the battlefield against the trend of the upgrade. Based on the actual combat conditions, this paper uses MATLAB to build the SINS model. Through the simulation of the model, the accuracy of the inertial navigation system under different maneuvering conditions is studied. Based on combat using inertial navigation performance assessment, design a more effective flight test. In order to relax the launch envelope and reduce the limit of aircraft attitude, and make some exploration to maximize the effectiveness of missile operations.