The traditional pseudorange single-point localization model is difficult to obtain high-precision positioning results and cannot meet the needs of modern application scenarios, because of factors such as model noise, orbit clock error accuracy and atmospheric error correction accuracy. In this paper, a pseudo-range single-point positioning method for regional atmospheric augmented is proposed, which can significantly improve the positioning performance. The algorithm uses precision orbit and clock products to reduce the satellite orbit clock error, uses regional atmospheric parameters to weaken the tropospheric ionospheric error, and uses dual-frequency uncombined model to reduce the noise of the observation model. The verification results of the measured data show that the positioning accuracy RMS of the regional atmospheric augmented pseudorange single-point positioning method is better than 0.2 meters in the horizontal direction and 0.25 meters in the elevation direction, the positioning accuracy is greatly improved. The sub-meter pseudo-range single-point positioning accuracy has important reference value in practical engineering applications